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Discovery of SARS-CoV-2-E channel inhibitors as antiviral candidates

Lack of efficiency has been a major problem shared by all currently developed anti-SARS-CoV-2 therapies. Our previous study shows that SARS-CoV-2 structural envelope (2-E) protein forms a type of cation channel, and heterogeneously expression of 2-E channels causes host cell death. In this study we...

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Detalles Bibliográficos
Autores principales: Wang, Yi, Fang, Sui, Wu, Yan, Cheng, Xi, Zhang, Lei-ke, Shen, Xu-rui, Li, Shuang-qu, Xu, Jian-rong, Shang, Wei-juan, Gao, Zhao-bing, Xia, Bing-qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295639/
https://www.ncbi.nlm.nih.gov/pubmed/34294887
http://dx.doi.org/10.1038/s41401-021-00732-2