Cargando…
Discovery of SARS-CoV-2-E channel inhibitors as antiviral candidates
Lack of efficiency has been a major problem shared by all currently developed anti-SARS-CoV-2 therapies. Our previous study shows that SARS-CoV-2 structural envelope (2-E) protein forms a type of cation channel, and heterogeneously expression of 2-E channels causes host cell death. In this study we...
Autores principales: | Wang, Yi, Fang, Sui, Wu, Yan, Cheng, Xi, Zhang, Lei-ke, Shen, Xu-rui, Li, Shuang-qu, Xu, Jian-rong, Shang, Wei-juan, Gao, Zhao-bing, Xia, Bing-qing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295639/ https://www.ncbi.nlm.nih.gov/pubmed/34294887 http://dx.doi.org/10.1038/s41401-021-00732-2 |
Ejemplares similares
-
Inhibitory Effects of Antiviral Drug Candidates on Canine Parvovirus in F81 cells
por: Zhou, Hongzhuan, et al.
Publicado: (2019) -
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease
por: Dai, Wenhao, et al.
Publicado: (2020) -
Antiviral Drug Discovery: Norovirus Proteases and Development of Inhibitors
por: Chang, Kyeong-Ok, et al.
Publicado: (2019) -
SARS-CoV-2: An Update on Potential Antivirals in Light of SARS-CoV Antiviral Drug Discoveries
por: Elshabrawy, Hatem A.
Publicado: (2020) -
Discovery of inhibitors against SARS-CoV-2 main protease using fragment-based drug design
por: Shao, Hai Ping, et al.
Publicado: (2023)