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Discovering antiviral restriction factors and pathways using genetic screens

Viral infections activate the powerful interferon (IFN) response that induces the expression of several hundred IFN stimulated genes (ISGs). The principal role of this extensive response is to create an unfavourable environment for virus replication and to limit spread; however, untangling the biolo...

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Detalles Bibliográficos
Autores principales: Jones, Chloe E., Tan, Wenfang S., Grey, Finn, Hughes, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295917/
https://www.ncbi.nlm.nih.gov/pubmed/34020727
http://dx.doi.org/10.1099/jgv.0.001603