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Intranasal Ketamine for Acute Pain: Behavioral and Neurophysiological Safety Analysis in Mice

BACKGROUND: Subanesthetic ketamine has been used for treatment-resistant depression and is popular as an opioid-sparing agent. OBJECTIVE: The present study aimed to investigate the dose-dependent antinociceptive effect of intranasal ketamine (INK) along with behavioral and neurophysiological safety...

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Detalles Bibliográficos
Autores principales: Goswami, Nidhi, Aleem, Mohd, Manda, Kailash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296084/
https://www.ncbi.nlm.nih.gov/pubmed/34306267
http://dx.doi.org/10.1016/j.curtheres.2021.100627