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MDM2/X Inhibitors as Radiosensitizers for Glioblastoma Targeted Therapy
Inhibition of the MDM2/X-p53 interaction is recognized as a potential anti-cancer strategy, including the treatment of glioblastoma (GB). In response to cellular stressors, such as DNA damage, the tumor suppression protein p53 is activated and responds by mediating cellular damage through DNA repair...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296304/ https://www.ncbi.nlm.nih.gov/pubmed/34307171 http://dx.doi.org/10.3389/fonc.2021.703442 |