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Sorting nexin-27 regulates AMPA receptor trafficking through the synaptic adhesion protein LRFN2

The endosome-associated cargo adaptor sorting nexin-27 (SNX27) is linked to various neuropathologies through sorting of integral proteins to the synaptic surface, most notably AMPA receptors. To provide a broader view of SNX27-associated pathologies, we performed proteomics in rat primary neurons to...

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Detalles Bibliográficos
Autores principales: McMillan, Kirsty J, Banks, Paul J, Hellel, Francesca LN, Carmichael, Ruth E, Clairfeuille, Thomas, Evans, Ashley J, Heesom, Kate J, Lewis, Philip, Collins, Brett M, Bashir, Zafar I, Henley, Jeremy M, Wilkinson, Kevin A, Cullen, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296521/
https://www.ncbi.nlm.nih.gov/pubmed/34251337
http://dx.doi.org/10.7554/eLife.59432