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Large-scale lipidomic profiling identifies novel potential biomarkers for prion diseases and highlights lipid raft-related pathways

Prion diseases are transmissible spongiform encephalopathies induced by the abnormally-folded prion protein (PrP(Sc)), which is derived from the normal prion protein (PrP(C)). Previous studies have reported that lipid rafts play a pivotal role in the conversion of PrP(C) into PrP(Sc), and several th...

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Detalles Bibliográficos
Autores principales: Kim, Yong-Chan, Lee, Junbeom, Lee, Dae-Weon, Jeong, Byung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296529/
https://www.ncbi.nlm.nih.gov/pubmed/34289911
http://dx.doi.org/10.1186/s13567-021-00975-1