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Large-scale lipidomic profiling identifies novel potential biomarkers for prion diseases and highlights lipid raft-related pathways
Prion diseases are transmissible spongiform encephalopathies induced by the abnormally-folded prion protein (PrP(Sc)), which is derived from the normal prion protein (PrP(C)). Previous studies have reported that lipid rafts play a pivotal role in the conversion of PrP(C) into PrP(Sc), and several th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296529/ https://www.ncbi.nlm.nih.gov/pubmed/34289911 http://dx.doi.org/10.1186/s13567-021-00975-1 |