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Antiangiogenic therapy reverses the immunosuppressive breast cancer microenvironment

Tumor angiogenesis induces local hypoxia and recruits immunosuppressive cells, whereas hypoxia subsequently promotes tumor angiogenesis. Immunotherapy efficacy depends on the accumulation and activity of tumor-infiltrating immune cells (TIICs). Antangiogenic therapy could improve local perfusion, re...

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Detalles Bibliográficos
Autores principales: Chen, Wuzhen, Shen, Lesang, Jiang, Jingxin, Zhang, Leyi, Zhang, Zhigang, Pan, Jun, Ni, Chao, Chen, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296533/
https://www.ncbi.nlm.nih.gov/pubmed/34294146
http://dx.doi.org/10.1186/s40364-021-00312-w