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Antiangiogenic therapy reverses the immunosuppressive breast cancer microenvironment
Tumor angiogenesis induces local hypoxia and recruits immunosuppressive cells, whereas hypoxia subsequently promotes tumor angiogenesis. Immunotherapy efficacy depends on the accumulation and activity of tumor-infiltrating immune cells (TIICs). Antangiogenic therapy could improve local perfusion, re...
Autores principales: | Chen, Wuzhen, Shen, Lesang, Jiang, Jingxin, Zhang, Leyi, Zhang, Zhigang, Pan, Jun, Ni, Chao, Chen, Zhigang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296533/ https://www.ncbi.nlm.nih.gov/pubmed/34294146 http://dx.doi.org/10.1186/s40364-021-00312-w |
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