hucMSC-derived exosomes attenuate colitis by regulating macrophage pyroptosis via the miR-378a-5p/NLRP3 axis

BACKGROUND: Human umbilical cord mesenchymal stem cell (hucMSC)-derived exosomes are recognized as novel cell-free therapeutic agents for inflammatory bowel disease (IBD), a condition caused by dysregulated intestinal mucosal immunity. In this event, macrophage pyroptosis, a process of cell death fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Xiu, Zhang, Zhi-yu, Yuan, Jin-tao, Ocansey, Dickson Kofi Wiredu, Tu, Qiang, Zhang, Xu, Qian, Hui, Xu, Wen-rong, Qiu, Wei, Mao, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296541/
https://www.ncbi.nlm.nih.gov/pubmed/34294138
http://dx.doi.org/10.1186/s13287-021-02492-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296541/
https://www.ncbi.nlm.nih.gov/pubmed/34294138
http://dx.doi.org/10.1186/s13287-021-02492-6

Ejemplares similares