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Causes of altered ventricular mechanics in hypertrophic cardiomyopathy: an in-silico study

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is typically caused by mutations in sarcomeric genes leading to cardiomyocyte disarray, replacement fibrosis, impaired contractility, and elevated filling pressures. These varying tissue properties are associated with certain strain patterns that may all...

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Detalles Bibliográficos
Autores principales: Kovacheva, Ekaterina, Gerach, Tobias, Schuler, Steffen, Ochs, Marco, Dössel, Olaf, Loewe, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296558/
https://www.ncbi.nlm.nih.gov/pubmed/34294108
http://dx.doi.org/10.1186/s12938-021-00900-9