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Causes of altered ventricular mechanics in hypertrophic cardiomyopathy: an in-silico study
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is typically caused by mutations in sarcomeric genes leading to cardiomyocyte disarray, replacement fibrosis, impaired contractility, and elevated filling pressures. These varying tissue properties are associated with certain strain patterns that may all...
Autores principales: | Kovacheva, Ekaterina, Gerach, Tobias, Schuler, Steffen, Ochs, Marco, Dössel, Olaf, Loewe, Axel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296558/ https://www.ncbi.nlm.nih.gov/pubmed/34294108 http://dx.doi.org/10.1186/s12938-021-00900-9 |
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