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Genome-wide DNA methylome analysis identifies methylation signatures associated with survival and drug resistance of ovarian cancers

BACKGROUND: In contrast to stable genetic events, epigenetic changes are highly plastic and play crucial roles in tumor evolution and development. Epithelial ovarian cancer (EOC) is a highly heterogeneous disease that is generally associated with poor prognosis and treatment failure. Profiling epige...

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Detalles Bibliográficos
Autores principales: Chan, David W., Lam, Wai-Yip, Chen, Fushun, Yung, Mingo M. H., Chan, Yau-Sang, Chan, Wai-Sun, He, Fangfang, Liu, Stephanie S., Chan, Karen K. L., Li, Benjamin, Ngan, Hextan Y. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296615/
https://www.ncbi.nlm.nih.gov/pubmed/34294135
http://dx.doi.org/10.1186/s13148-021-01130-5