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Genome-wide DNA methylome analysis identifies methylation signatures associated with survival and drug resistance of ovarian cancers
BACKGROUND: In contrast to stable genetic events, epigenetic changes are highly plastic and play crucial roles in tumor evolution and development. Epithelial ovarian cancer (EOC) is a highly heterogeneous disease that is generally associated with poor prognosis and treatment failure. Profiling epige...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296615/ https://www.ncbi.nlm.nih.gov/pubmed/34294135 http://dx.doi.org/10.1186/s13148-021-01130-5 |