Cargando…

Development of a Rapid In Vitro Screening Assay Using Metabolic Inhibitors to Detect Highly Selective Anticancer Agents

[Image: see text] Traditional long exposure (24–72 h) cell viability assays for identification of potential drug compounds can fail to identify compounds that are: (a) biologically active but not toxic and (b) inactive without the addition of a synergistic additive. Herein, we report the development...

Descripción completa

Detalles Bibliográficos
Autores principales: Abebe, Felagot A., Hopkins, Megan D., Vodnala, Suraj N., Sheaff, Robert J., Lamar, Angus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296616/
https://www.ncbi.nlm.nih.gov/pubmed/34308064
http://dx.doi.org/10.1021/acsomega.1c02203