Control of Multigene Expression Stoichiometry in Mammalian Cells Using Synthetic Promoters

[Image: see text] To successfully engineer mammalian cells for a desired purpose, multiple recombinant genes are required to be coexpressed at a specific and optimal ratio. In this study, we hypothesized that synthetic promoters varying in transcriptional activity could be used to create single mult...

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Detalles Bibliográficos
Autores principales: Patel, Yash D., Brown, Adam J., Zhu, Jie, Rosignoli, Guglielmo, Gibson, Suzanne J., Hatton, Diane, James, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296667/
https://www.ncbi.nlm.nih.gov/pubmed/33939428
http://dx.doi.org/10.1021/acssynbio.0c00643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296667/
https://www.ncbi.nlm.nih.gov/pubmed/33939428
http://dx.doi.org/10.1021/acssynbio.0c00643

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