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A review of Dynamin 2 involvement in cancers highlights a promising therapeutic target

Dynamin 2 (DNM2) is an ubiquitously expressed large GTPase well known for its role in vesicle formation in endocytosis and intracellular membrane trafficking also acting as a regulator of cytoskeletons. During the last two decades, DNM2 involvement, through mutations or overexpression, emerged in an...

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Detalles Bibliográficos
Autores principales: Trochet, Delphine, Bitoun, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296698/
https://www.ncbi.nlm.nih.gov/pubmed/34294140
http://dx.doi.org/10.1186/s13046-021-02045-y