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Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated autophagy

BACKGROUND: Intracerebral hemorrhage (ICH) is a major public health concern, and mesenchymal stem cells (MSCs) hold great potential for treating ICH. However, the quantity and quality of MSCs decline in the cerebral niche, limiting the potential efficacy of MSCs. Hypoxic preconditioning is suggested...

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Detalles Bibliográficos
Autores principales: Liu, Jianyang, He, Jialin, Ge, Lite, Xiao, Han, Huang, Yan, Zeng, Liuwang, Jiang, Zheng, Lu, Ming, Hu, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296710/
https://www.ncbi.nlm.nih.gov/pubmed/34294127
http://dx.doi.org/10.1186/s13287-021-02480-w