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A CREB1-miR-181a-5p loop regulates the pathophysiologic features of bone marrow stromal cells in fibrous dysplasia of bone

BACKGROUND: Fibrous dysplasia (FD) is a bone marrow stromal cell (BMSC) disease caused by activating mutations of guanine nucleotide-binding protein alpha-stimulating activity polypeptide (GNAS) and is characterized by increased proliferative activity and disrupted osteogenesis of BMSCs. However, th...

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Detalles Bibliográficos
Autores principales: Fu, Yu, Xin, Zhili, Ling, Ziji, Xie, Hanyu, Xiao, Tao, Shen, Xin, Lin, Jialin, Xu, Ling, Jiang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296714/
https://www.ncbi.nlm.nih.gov/pubmed/34294046
http://dx.doi.org/10.1186/s10020-021-00341-z