Single nucleotide replacement in the Atlantic salmon genome using CRISPR/Cas9 and asymmetrical oligonucleotide donors

BACKGROUND: New breeding technologies (NBT) using CRISPR/Cas9-induced homology directed repair (HDR) has the potential to expedite genetic improvement in aquaculture. The long generation time in Atlantic salmon makes breeding an unattractive solution to obtain homozygous mutants and improving the ra...

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Detalles Bibliográficos
Autores principales: Straume, Anne Hege, Kjærner-Semb, Erik, Skaftnesmo, Kai Ove, Güralp, Hilal, Lillico, Simon, Wargelius, Anna, Edvardsen, Rolf Brudvik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296724/
https://www.ncbi.nlm.nih.gov/pubmed/34294050
http://dx.doi.org/10.1186/s12864-021-07823-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296724/
https://www.ncbi.nlm.nih.gov/pubmed/34294050
http://dx.doi.org/10.1186/s12864-021-07823-8

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