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Extracellular vesicles derived from mesenchymal stromal cells mediate endogenous cell growth and migration via the CXCL5 and CXCL6/CXCR2 axes and repair menisci

BACKGROUND: Mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) are promising candidates for tissue regeneration therapy. However, the therapeutic efficacy of MSC-EVs for meniscus regeneration is uncertain, and the mechanisms underlying MSC-EV-mediated tissue regeneration have not been...

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Detalles Bibliográficos
Autores principales: Kawata, Kazumasa, Koga, Hideyuki, Tsuji, Kunikazu, Miyatake, Kazumasa, Nakagawa, Yusuke, Yokota, Takanori, Sekiya, Ichiro, Katagiri, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296733/
https://www.ncbi.nlm.nih.gov/pubmed/34294118
http://dx.doi.org/10.1186/s13287-021-02481-9