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Abnormal methylation characteristics predict chemoresistance and poor prognosis in advanced high-grade serous ovarian cancer

BACKGROUND: Primary or acquired chemoresistance is a key link in the high mortality rate of ovarian cancer. There is no reliable method to predict chemoresistance in ovarian cancer. We hypothesized that specific methylation characteristics could distinguish chemoresistant and chemosensitive ovarian...

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Detalles Bibliográficos
Autores principales: Feng, Li-yuan, Yan, Bing-bing, Huang, Yong-zhi, Li, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296752/
https://www.ncbi.nlm.nih.gov/pubmed/34289901
http://dx.doi.org/10.1186/s13148-021-01133-2