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Bruton’s Tyrosine Kinase and Its Isoforms in Cancer

Bruton’s tyrosine kinase (BTK) is a soluble tyrosine kinase with central roles in the development, maturation, and signaling of B cells. BTK has been found to regulate cell proliferation, survival, and migration in various B-cell malignancies. Targeting BTK with recently developed BTK inhibitors has...

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Detalles Bibliográficos
Autores principales: Wang, Xianhui, Kokabee, Leila, Kokabee, Mostafa, Conklin, Douglas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297165/
https://www.ncbi.nlm.nih.gov/pubmed/34307353
http://dx.doi.org/10.3389/fcell.2021.668996