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Bruton’s Tyrosine Kinase and Its Isoforms in Cancer
Bruton’s tyrosine kinase (BTK) is a soluble tyrosine kinase with central roles in the development, maturation, and signaling of B cells. BTK has been found to regulate cell proliferation, survival, and migration in various B-cell malignancies. Targeting BTK with recently developed BTK inhibitors has...
Autores principales: | Wang, Xianhui, Kokabee, Leila, Kokabee, Mostafa, Conklin, Douglas S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297165/ https://www.ncbi.nlm.nih.gov/pubmed/34307353 http://dx.doi.org/10.3389/fcell.2021.668996 |
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