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Transcriptomic Profiling of Control and Thyroid-Associated Orbitopathy (TAO) Orbital Fat and TAO Orbital Fibroblasts Undergoing Adipogenesis

PURPOSE: Orbital fat hyperplasia commonly occurs in thyroid-associated orbitopathy (TAO). To understand molecular mechanisms underlying orbital adipogenesis, we used transcriptomics to compare gene expression in controls and patients with TAO, as well as in orbital fibroblasts (OFs) undergoing adipo...

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Detalles Bibliográficos
Autores principales: Kim, Dong Won, Taneja, Kamil, Hoang, Thanh, Santiago, Clayton P., McCulley, Timothy J., Merbs, Shannath L., Mahoney, Nicholas R., Blackshaw, Seth, Rajaii, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297424/
https://www.ncbi.nlm.nih.gov/pubmed/34269815
http://dx.doi.org/10.1167/iovs.62.9.24