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Mechanisms of Action of the New Antibodies in Use in Multiple Myeloma

Monoclonal antibodies (mAbs) directed against antigen-specific of multiple myeloma (MM) cells have Fc-dependent immune effector mechanisms, such as complement-dependent cytotoxicity (CDC), antibody-dependent cellular cytotoxicity (ADCC), and antibody-dependent cellular phagocytosis (ADCP), but the c...

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Detalles Bibliográficos
Autores principales: Romano, Alessandra, Storti, Paola, Marchica, Valentina, Scandura, Grazia, Notarfranchi, Laura, Craviotto, Luisa, Di Raimondo, Francesco, Giuliani, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297441/
https://www.ncbi.nlm.nih.gov/pubmed/34307150
http://dx.doi.org/10.3389/fonc.2021.684561