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Dynamic regulation of B cell Complement Signaling is Integral to Germinal Center Responses
B cell maturation within germinal centers (GCs) generates diversified B cell pools and high-affinity B cell antigen receptors (BCRs) for pathogen clearance. Increased receptor affinity is achieved by iterative cycles of T cell-dependent, affinity-based B cell positive selection and clonal expansion...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297556/ https://www.ncbi.nlm.nih.gov/pubmed/34031614 http://dx.doi.org/10.1038/s41590-021-00926-0 |