PAK1 Mediates Bone Marrow Stromal Cell-Induced Drug Resistance in Acute Myeloid Leukemia via ERK1/2 Signaling Pathway

BACKGROUND: Chemoresistance is emerging as a major barrier to successful treatment in acute myeloid leukemia (AML), and bone marrow stromal cells (BMSCs) protect leukemia cells from chemotherapy eventually leading to recurrence. This study was designed to investigate the role of p21-activated kinase...

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Detalles Bibliográficos
Autores principales: Li, Banban, Jia, Ruinan, Li, Wei, Zhou, Ying, Guo, Dongmei, Teng, Qingliang, Du, Shenghong, Li, Mingying, Li, Wěi, Sun, Tao, Ma, Daoxin, Ji, Min, Ji, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297649/
https://www.ncbi.nlm.nih.gov/pubmed/34307365
http://dx.doi.org/10.3389/fcell.2021.686695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297649/
https://www.ncbi.nlm.nih.gov/pubmed/34307365
http://dx.doi.org/10.3389/fcell.2021.686695

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