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SOCS3 deficiency in cardiomyocytes elevates sensitivity of ischemic preconditioning that synergistically ameliorates myocardial ischemia reperfusion injury

Ischemic preconditioning (IPC) is the most powerful endogenous cardioprotective form of cellular adaptation. However, the inhibitory or augmenting mechanism underlying cardioprotection via IPC remains largely unknown. Suppressor of cytokine signaling-3 (SOCS3) is a cytokine-inducible potent negative...

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Detalles Bibliográficos
Autores principales: Nohara, Shoichiro, Yamamoto, Mai, Yasukawa, Hideo, Nagata, Takanobu, Takahashi, Jinya, Shimozono, Koutatsu, Yanai, Toshiyuki, Sasaki, Tomoko, Okabe, Kota, Shibata, Tatsuhiro, Akagaki, Daiki, Mawatari, Kazutoshi, Fukumoto, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297769/
https://www.ncbi.nlm.nih.gov/pubmed/34292971
http://dx.doi.org/10.1371/journal.pone.0254712