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Collagen XVII inhibits breast cancer cell proliferation and growth through deactivation of the AKT/mTOR signaling pathway

Collagen XVII (COL17), a cell-matrix adhesion protein, has been found to be suppressed in breast cancer. Our previous data demonstrated a preventive role of COL17 in breast cancer invasiveness. The present study used the stable COL17-overexpressing MCF7 and MDA-MB-231 cells to reveal an anti-prolife...

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Detalles Bibliográficos
Autores principales: Lothong, Muttarin, Sakares, Watchara, Rojsitthisak, Pornchai, Tanikawa, Chizu, Matsuda, Koichi, Yodsurang, Varalee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297889/
https://www.ncbi.nlm.nih.gov/pubmed/34293053
http://dx.doi.org/10.1371/journal.pone.0255179