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Enantiospecific antitrypanosomal in vitro activity of eflornithine

The polyamine synthesis inhibitor eflornithine is a recommended treatment for the neglected tropical disease Gambian human African trypanosomiasis in late stage. This parasitic disease, transmitted by the tsetse fly, is lethal unless treated. Eflornithine is administered by repeated intravenous infu...

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Detalles Bibliográficos
Autores principales: Boberg, Mikael, Cal, Monica, Kaiser, Marcel, Jansson-Löfmark, Rasmus, Mäser, Pascal, Ashton, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297939/
https://www.ncbi.nlm.nih.gov/pubmed/34252098
http://dx.doi.org/10.1371/journal.pntd.0009583