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Ufbp1, a Key Player of Ufm1 Conjugation System, Protects Against Ketosis-Induced Liver Injury via Suppressing Smad3 Activation

The dairy cattle suffer from severe liver dysfunction during the pathogenesis of ketosis. The Ufm1 conjugation system is crucial for liver development and homeostasis. Ufm1 binding protein (Ufbp1) is a putative Ufm1 target and an integral component, but its role in ketosis-induced liver injury is un...

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Detalles Bibliográficos
Autores principales: Chen, Fanghui, Sheng, Le, Xu, Chenjie, Li, Jun, Ali, Ilyas, Li, Honglin, Cai, Yafei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297976/
https://www.ncbi.nlm.nih.gov/pubmed/34307359
http://dx.doi.org/10.3389/fcell.2021.676789