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Cryo-EM structures of the caspase-activated protein XKR9 involved in apoptotic lipid scrambling

The exposure of the negatively charged lipid phosphatidylserine on the cell surface, catalyzed by lipid scramblases, is an important signal for the clearance of apoptotic cells by macrophages. The protein XKR9 is a member of a conserved family that has been associated with apoptotic lipid scrambling...

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Detalles Bibliográficos
Autores principales: Straub, Monique S, Alvadia, Carolina, Sawicka, Marta, Dutzler, Raimund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298096/
https://www.ncbi.nlm.nih.gov/pubmed/34263724
http://dx.doi.org/10.7554/eLife.69800