Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor

Glucose-dependent insulinotropic polypeptide (GIP) is a peptide hormone that exerts crucial metabolic functions by binding and activating its cognate receptor, GIPR. As an important therapeutic target, GIPR has been subjected to intensive structural studies without success. Here, we report the cryo-...

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Detalles Bibliográficos
Autores principales: Zhao, Fenghui, Zhang, Chao, Zhou, Qingtong, Hang, Kaini, Zou, Xinyu, Chen, Yan, Wu, Fan, Rao, Qidi, Dai, Antao, Yin, Wanchao, Shen, Dan-Dan, Zhang, Yan, Xia, Tian, Stevens, Raymond C, Xu, H Eric, Yang, Dehua, Zhao, Lihua, Wang, Ming-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298097/
https://www.ncbi.nlm.nih.gov/pubmed/34254582
http://dx.doi.org/10.7554/eLife.68719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298097/
https://www.ncbi.nlm.nih.gov/pubmed/34254582
http://dx.doi.org/10.7554/eLife.68719

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