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Low Levels of MicroRNA-10a in Cardiovascular Endothelium and Blood Serum Are Related to Human Atherosclerotic Disease

BACKGROUND: MicroRNA-10a (miR-10a) inhibits transcriptional factor GATA6 to repress inflammatory GATA6/VCAM-1 signaling, which is regulated by blood flow to affect endothelial function/dysfunction. This study aimed to identify the expression patterns of miR-10a/GATA6/VCAM-1 in vivo and study their i...

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Detalles Bibliográficos
Autores principales: Kuo, Jong-Tar, Tsai, Hsiao-En, Lin, Ching-Ting, Lee, Chih-I, Lee, Pei-Ling, Ruan, Yu-Rong, Chiu, Jeng-Jiann, Lee, Ding-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298183/
https://www.ncbi.nlm.nih.gov/pubmed/34336268
http://dx.doi.org/10.1155/2021/1452917