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Low Levels of MicroRNA-10a in Cardiovascular Endothelium and Blood Serum Are Related to Human Atherosclerotic Disease
BACKGROUND: MicroRNA-10a (miR-10a) inhibits transcriptional factor GATA6 to repress inflammatory GATA6/VCAM-1 signaling, which is regulated by blood flow to affect endothelial function/dysfunction. This study aimed to identify the expression patterns of miR-10a/GATA6/VCAM-1 in vivo and study their i...
Autores principales: | Kuo, Jong-Tar, Tsai, Hsiao-En, Lin, Ching-Ting, Lee, Chih-I, Lee, Pei-Ling, Ruan, Yu-Rong, Chiu, Jeng-Jiann, Lee, Ding-Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298183/ https://www.ncbi.nlm.nih.gov/pubmed/34336268 http://dx.doi.org/10.1155/2021/1452917 |
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