C/EBPβ is a MYB- and p300-cooperating pro-leukemogenic factor and promising drug target in acute myeloid leukemia

Transcription factor MYB has recently emerged as a promising drug target for the treatment of acute myeloid leukemia (AML). Here, we have characterized a group of natural sesquiterpene lactones (STLs), previously shown to suppress MYB activity, for their potential to decrease AML cell proliferation....

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Detalles Bibliográficos
Autores principales: Yusenko, Maria V., Trentmann, Amke, Casolari, Debora A., Abdel Ghani, Luca, Lenz, Mairin, Horn, Melanie, Dörner, Wolfgang, Klempnauer, Stefan, Mootz, Henning D., Arteaga, Maria Francisca, Mikesch, Jan-Henrik, D’Andrea, Richard J., Gonda, Thomas J., Müller-Tidow, Carsten, Schmidt, Thomas J., Klempnauer, Karl-Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298201/
https://www.ncbi.nlm.nih.gov/pubmed/33958723
http://dx.doi.org/10.1038/s41388-021-01800-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298201/
https://www.ncbi.nlm.nih.gov/pubmed/33958723
http://dx.doi.org/10.1038/s41388-021-01800-x

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