Pharmacokinetics of Intraperitoneally Delivered Glucagon in Pigs: A Hypothesis of First Pass Metabolism

BACKGROUND AND OBJECTIVE: Artificial pancreases administering low-dose glucagon in addition to insulin have the scope to improve glucose control in patients with diabetes mellitus type 1. If such a device were to deliver both hormones intraperitoneally, it would mimic normal physiology, which may be...

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Detalles Bibliográficos
Autores principales: Teigen, Ingrid Anna, Åm, Marte Kierulf, Carlsen, Sven Magnus, Christiansen, Sverre Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298214/
https://www.ncbi.nlm.nih.gov/pubmed/34100220
http://dx.doi.org/10.1007/s13318-021-00692-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298214/
https://www.ncbi.nlm.nih.gov/pubmed/34100220
http://dx.doi.org/10.1007/s13318-021-00692-2

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