Role of hepcidin in oxidative stress and cell death of cultured mouse renal collecting duct cells: protection against iron and sensitization to cadmium

The liver hormone hepcidin regulates systemic iron homeostasis. Hepcidin is also expressed by the kidney, but exclusively in distal nephron segments. Several studies suggest hepcidin protects against kidney damage involving Fe(2+) overload. The nephrotoxic non-essential metal ion Cd(2+) can displace...

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Detalles Bibliográficos
Autores principales: Probst, Stephanie, Fels, Johannes, Scharner, Bettina, Wolff, Natascha A., Roussa, Eleni, van Swelm, Rachel P. L., Lee, Wing-Kee, Thévenod, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Molecular Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298330/
https://www.ncbi.nlm.nih.gov/pubmed/34181029
http://dx.doi.org/10.1007/s00204-021-03106-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298330/
https://www.ncbi.nlm.nih.gov/pubmed/34181029
http://dx.doi.org/10.1007/s00204-021-03106-z

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