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Role of hepcidin in oxidative stress and cell death of cultured mouse renal collecting duct cells: protection against iron and sensitization to cadmium
The liver hormone hepcidin regulates systemic iron homeostasis. Hepcidin is also expressed by the kidney, but exclusively in distal nephron segments. Several studies suggest hepcidin protects against kidney damage involving Fe(2+) overload. The nephrotoxic non-essential metal ion Cd(2+) can displace...
Autores principales: | Probst, Stephanie, Fels, Johannes, Scharner, Bettina, Wolff, Natascha A., Roussa, Eleni, van Swelm, Rachel P. L., Lee, Wing-Kee, Thévenod, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298330/ https://www.ncbi.nlm.nih.gov/pubmed/34181029 http://dx.doi.org/10.1007/s00204-021-03106-z |
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