An epigenetic GPI anchor defect impairs TLR4 signaling in the B cell transdifferentiation model for primary human monocytes BLaER1

Antigen-presenting myeloid cells like monocytes detect invading pathogens via pattern recognition receptors (PRRs) and initiate adaptive and innate immune responses. As analysis of PRR signaling in primary human monocytes is hampered by their restricted expandability, human monocyte models like THP-...

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Detalles Bibliográficos
Autores principales: Wegner, Julia, Zillinger, Thomas, Schlee-Guimaraes, Thais Marina, Bartok, Eva, Schlee, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298422/
https://www.ncbi.nlm.nih.gov/pubmed/34294787
http://dx.doi.org/10.1038/s41598-021-94386-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298422/
https://www.ncbi.nlm.nih.gov/pubmed/34294787
http://dx.doi.org/10.1038/s41598-021-94386-z

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