Generation and first characterization of TRDC-knockout pigs lacking γδ T cells

The TRDC-locus encodes the T cell receptor delta constant region, one component of the γδ T cell receptor which is essential for development of γδ T cells. In contrast to peptide recognition by αβ T cells, antigens activating γδ T cells are mostly MHC independent and not well characterized. Therefor...

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Detalles Bibliográficos
Autores principales: Petersen, Bjoern, Kammerer, Robert, Frenzel, Antje, Hassel, Petra, Dau, Tung Huy, Becker, Roswitha, Breithaupt, Angele, Ulrich, Reiner Georg, Lucas-Hahn, Andrea, Meyers, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298467/
https://www.ncbi.nlm.nih.gov/pubmed/34294758
http://dx.doi.org/10.1038/s41598-021-94017-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298467/
https://www.ncbi.nlm.nih.gov/pubmed/34294758
http://dx.doi.org/10.1038/s41598-021-94017-7

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