Topoisomerase II deficiency leads to a postreplicative structural shift in all Saccharomyces cerevisiae chromosomes

The key role of Topoisomerase II (Top2) is the removal of topological intertwines between sister chromatids. In yeast, inactivation of Top2 brings about distinct cell cycle responses. In the case of the conditional top2-5 allele, interphase and mitosis progress on schedule but cells suffer from a ch...

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Detalles Bibliográficos
Autores principales: Ayra-Plasencia, Jessel, Ramos-Pérez, Cristina, Santana-Sosa, Silvia, Quevedo, Oliver, Medina-Suárez, Sara, Matos-Perdomo, Emiliano, Zamora-Dorta, Marcos, Brown, Grant W., Lisby, Michael, Machín, Félix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298500/
https://www.ncbi.nlm.nih.gov/pubmed/34294749
http://dx.doi.org/10.1038/s41598-021-93875-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298500/
https://www.ncbi.nlm.nih.gov/pubmed/34294749
http://dx.doi.org/10.1038/s41598-021-93875-5

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