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Guanylate-binding proteins induce apoptosis of leukemia cells by regulating MCL-1 and BAK
Interferon-inducible guanylate-binding proteins (GBPs) are well-known for mediating host-defense mechanisms against cellular pathogens. Emerging evidence suggests that GBPs are also implicated in tumorigenesis; however, their underlying molecular mechanism is still unknown. In this study, we identif...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298518/ https://www.ncbi.nlm.nih.gov/pubmed/34294680 http://dx.doi.org/10.1038/s41389-021-00341-y |