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Guanylate-binding proteins induce apoptosis of leukemia cells by regulating MCL-1 and BAK

Interferon-inducible guanylate-binding proteins (GBPs) are well-known for mediating host-defense mechanisms against cellular pathogens. Emerging evidence suggests that GBPs are also implicated in tumorigenesis; however, their underlying molecular mechanism is still unknown. In this study, we identif...

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Detalles Bibliográficos
Autores principales:	Luo, Yongyang, Jin, Hanyong, Kim, Je Hyeong, Bae, Jeehyeon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298518/ https://www.ncbi.nlm.nih.gov/pubmed/34294680 http://dx.doi.org/10.1038/s41389-021-00341-y

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