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A machine learning approach to brain epigenetic analysis reveals kinases associated with Alzheimer’s disease

Alzheimer’s disease (AD) is influenced by both genetic and environmental factors; thus, brain epigenomic alterations may provide insights into AD pathogenesis. Multiple array-based Epigenome-Wide Association Studies (EWASs) have identified robust brain methylation changes in AD; however, array-based...

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Detalles Bibliográficos
Autores principales: Huang, Yanting, Sun, Xiaobo, Jiang, Huige, Yu, Shaojun, Robins, Chloe, Armstrong, Matthew J., Li, Ronghua, Mei, Zhen, Shi, Xiaochuan, Gerasimov, Ekaterina Sergeevna, De Jager, Philip L., Bennett, David A., Wingo, Aliza P., Jin, Peng, Wingo, Thomas S., Qin, Zhaohui S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298578/
https://www.ncbi.nlm.nih.gov/pubmed/34294691
http://dx.doi.org/10.1038/s41467-021-24710-8