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Quantifying the contribution of Neanderthal introgression to the heritability of complex traits

Eurasians have ~2% Neanderthal ancestry, but we lack a comprehensive understanding of the genome-wide influence of Neanderthal introgression on modern human diseases and traits. Here, we quantify the contribution of introgressed alleles to the heritability of more than 400 diverse traits. We show th...

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Detalles Bibliográficos
Autores principales: McArthur, Evonne, Rinker, David C., Capra, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298587/
https://www.ncbi.nlm.nih.gov/pubmed/34294692
http://dx.doi.org/10.1038/s41467-021-24582-y