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Cannabis constituents interact at the drug efflux pump BCRP to markedly increase plasma cannabidiolic acid concentrations

Cannabis is a complex mixture of hundreds of bioactive molecules. This provides the potential for pharmacological interactions between cannabis constituents, a phenomenon referred to as “the entourage effect” by the medicinal cannabis community. We hypothesize that pharmacokinetic interactions betwe...

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Detalles Bibliográficos
Autores principales: Anderson, Lyndsey L., Etchart, Maia G., Bahceci, Dilara, Golembiewski, Taliesin A., Arnold, Jonathon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298633/
https://www.ncbi.nlm.nih.gov/pubmed/34294753
http://dx.doi.org/10.1038/s41598-021-94212-6