Context-dependent effects of whole-genome duplication during mammary tumor recurrence

Whole-genome duplication (WGD) generates polyploid cells possessing more than two copies of the genome and is among the most common genetic abnormalities in cancer. The frequency of WGD increases in advanced and metastatic tumors, and WGD is associated with poor prognosis in diverse tumor types, sug...

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Detalles Bibliográficos
Autores principales: Newcomb, Rachel, Dean, Emily, McKinney, Brock J., Alvarez, James V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298634/
https://www.ncbi.nlm.nih.gov/pubmed/34294755
http://dx.doi.org/10.1038/s41598-021-94332-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298634/
https://www.ncbi.nlm.nih.gov/pubmed/34294755
http://dx.doi.org/10.1038/s41598-021-94332-z

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