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Targeting Neuroinflammation via Purinergic P2 Receptors for Disease Modification in Drug-Refractory Epilepsy

Treatment of epilepsy remains a clinical challenge, with >30% of patients not responding to current antiseizure drugs (ASDs). Moreover, currently available ASDs are merely symptomatic without altering significantly the progression of the disease. Inflammation is increasingly recognized as playing...

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Detalles Bibliográficos
Autores principales: Engel, Tobias, Smith, Jonathon, Alves, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298823/
https://www.ncbi.nlm.nih.gov/pubmed/34305404
http://dx.doi.org/10.2147/JIR.S287740